Method manuscript
Quant Group, et al. A Bayesian model for quantifying genomic variant evidence sufficiency in Mendelian disease. medRxiv (2025). DOI: https://doi.org/10.64898/2025.12.02.25341503.
Press kit
QuantBayes Studio
QuantBayes Studio is evidence verification infrastructure for scientific, clinical, technical, and AI workflows. It helps teams define evidence requirements, check available evidence, quantify evidence sufficiency, and preserve an auditable result trail.
QuantBayes Studio is developed and operated by Switzerland Omics. It builds on the open source QuantBayes Engine, a Bayesian evidence sufficiency method first developed for clinical genomics and released under the MIT licence.
Press assets
| Asset | Description | Download |
|---|---|---|
| QuantBayes Studio logo | Primary product logo for web and print use. | Download logo |
| Product screenshots | Interface screenshots for profiles, cases, evidence matrices, runs, reports, and API workflows. | Download screenshots |
| Storyboard | Visual explanation of evidence-based conclusions using the pie, dog, and alien analogy. | Download storyboard |
| Method references | Academic and software references for the open source QuantBayes Engine. | View citations |
Use the product name as “QuantBayes Studio”. The open source statistical engine should be referred to as “QuantBayes Engine” or “QuantBayes”.
Product summary
QuantBayes Studio separates a conclusion from the evidence trail behind it. A user, team, or community defines an evidence profile stating what must be checked before a result is trusted. Each case is evaluated against that profile, including missing evidence and contradictions. The QuantBayes Engine then computes an evidence sufficiency score with uncertainty, while Studio preserves the profile, evidence matrix, run, report, and audit trail.
The platform does not decide whether a claim is true. It measures how much declared evidence is available under a stated rule set, making results easier to inspect, compare, and reuse across teams, pipelines, and institutions.
Suggested citation
Software archive
QuantBayes software archive, Zenodo: https://doi.org/10.5281/zenodo.17919369
R package
QuantBayes R package, CRAN: https://doi.org/10.32614/CRAN.package.quantbayes
Operator
QuantBayes Studio is a Switzerland Omics product that reimplements the open source QuantBayes evidence sufficiency engine.